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The Closest Human Evidence and It Was Negative There is no human Dihexa trial, but the same HGF/c-Met drug program did reach human testing through Athira Pharma's fosgonimeton (ATH-1017)

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To further build upon the promising findings from prior studies, future investigations should focus on large-scale, multicenter clinical trials to rigorously assess the therapeutic effectiveness of phytochemicals like quercetin, curcumol, apigenin, boswellic acid and others, in treating IC induced by chemotherapy agents like cyclophosphamide and ifosfamide

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2a) indicated an AUC of 0.911 (95% CI 0.8580.964)