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Research indicates that the analgesic effect of rosemary essential oil in mice, particularly at a dose of 300 L/kg, is likely mediated through the NO/cGMP/K ATP signaling pathway (Hajhashemi et al., 2023)

A review of B12 studies for neuropathic pain found positive results

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409,410 This holds promise for developing novel therapeutic strategies targeting the gut microbiota to manage DPN effectively

Some animals were removed in each study (see ESM Methods: Animals before and after exclusion, and ESM Fig