The method of embodiment 21, wherein the thiophene carboxamide is a compound of Formula (I), Formula (II), Formula (III), Formula (IV), Formula (V), Formula (VI), Formula (VII), Formula (VIII), Formula (IX), Formula (X) or Formula (XI)
SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production
10.1016/j.eclinm.2024.102884 eClinicalMedicine
In addition, high intake of vitamin C increases excretion of uric acid (urate) and oxalic acid (oxalate)
*Archives of pharmacal research* , 30 (7), 834-839.
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