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85, 23242 doi: 10.1016/j.neuropharm.2014.05.027 111 LiuJ.FengX.WangY.XiaX.ZhengJ

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Statins Trigger Mitochondrial Reactive Oxygen Species-Induced Apoptosis in Glycolytic Skeletal Muscle

The E configuration is predominant in nature, better absorbed and spans the membrane more efficiently than any of the Z-isomers, most common in synthetic astaxanthin

However, oxidative stress happens when the antioxidant defense system of body is overwhelmed by the production of ROS ( Figure 1 )