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RPMI-1640 medium with 10% foetal bovine serum (FBS) (F7524, Sigma Aldrich) was added and mixed vigorously for 20 seconds to stop the reaction

Cochlear HCs contain the antioxidant glutathione, which is the substrate by which glutathione transferases detoxify ROS

How Glutathione May Support Liver Detoxification Your liver operates as a two-stage filtration system

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122,123,124 Mammalian CYPs are a family of heme-containing NAD(P)H-dependent monooxygenases that metabolize numerous endogenous metabolites, including fatty acids and steroids, and exogenous substrates, including carcinogens, pesticides and drugs, resulting in continuous production of ROS

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