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Studies have shown measurable bone density changes in as little as 12 months of treatment

During the first year, between 60% to 80% of patients with type 2 diabetes experience major improvement or remission

Similar results were seen in patients who had originally taken Wegovy, with those taking a placebo pill regaining 62% of their lost body weight, compared to 21% weight regain in those taking orforglipron

All of this is trial data, not a safety guarantee

Cardiovascular/metabolic benefits: Some large studies found that GLP-1s reduce the risk of major cardiovascular events, and may improve fatty-liver disease and other metabolic markers

To stay comfortable, its important to drink plenty of water and pay attention to the amount of fiber you consume each day