In this context, a patient who had food poisoning months earlier may already be at increased risk for microbial overgrowth, and additional slowing of gut motility (such as that associated with GLP-1 therapy) could further compound that risk
It is fairly quickly cleared from the circulation, though, with a half-life of around 30 minutes
A 2021 study published in Nature Microbiology identified a specific protein, called P9, that is secreted by Akkermansia and was shown to directly stimulate GLP-1 release from intestinal L-cells in mice
What semaglutide does and does not do to ketone production This is worth addressing directly because there is a persistent misconception
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