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Aust G, Sittig D, Steinert M, Lamesch P, Lohmann T

KL1 also reduced ROS/RNS in uninfected macrophages, highlighting its ability to modulate the host environment (Extended Data Fig

It neutralizes toxins, reduces oxidative stress, and repairs damaged cells

We found the majority were downregulated in viruliferous BLHs (56%)

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159 SIRT1 alleviates ER stress by deacetylating molecules such as eIF2 and CHOP, 32 inhibiting excessive activation of the unfolded protein response, 160 and reducing expression of stress-related proteins including GRP78 and ATF4