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PMID: 25243545

Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial

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63 Building on this approach, Pathway-Level Information Extractor (PLIER) further integrates biological priors, such as pathway and marker gene sets, to improve interpretability and separate biological variation from technical noise particularly valuable for aging muscle tissue, in which subtle transcriptomic shifts are challenging to resolve

365 The primary endpoint was not achieved

Additionally, it corroborated the amino acid dysregulation, evidencing a downregulation of valine and an upregulation of serine, leucine, and lysine in the pathological tissue