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In line with the activation of GcgR increasing systemic glucose levels, hyperglucagonemia is a hallmark occurrence associated with (non)fasted hyperglycemic exacerbation in obese and insulin resistant conditions [170]

Edited by Professor Massimiliano Agostini Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made

The result: fat that's mobilized is actually eliminated, and the rate of new fat accumulation in treated areas slows simultaneously

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38 , e102147 (2019)

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