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Although superoxide anions are relatively weak oxidants with limited chemical reactivity, they can generate more hazardous species, such as 1 O 2 and OH, which are known to cause lipid peroxidation (Halliwell and Chirico 1993)

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148 Kaempferol inhibits HMGB1 and TLR4 and downregulates NLRP3 expression, reducing proinflammatory cytokine levels and preventing APAP hepatotoxicity

Monitoring symptoms and working closely with a doctor are crucial for managing these risks while benefiting from the medication