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Based on RNA-seq data from MASLD model mice, we identified HBEGF , CFD , ADM , CCL19 , and LAMA2 as potential hepatokines that might mediate the effects of MASLD on sarcopenia (Fig

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The release of cytokines, which are effective regulators of inflammatory responses, stimulates the secretion of many glycoproteins, such as C-reactive protein, from the liver

That could give the tissue more fuel to heal, Chen says.