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By contrast, folinic acid can yield 5,10-methyl-THF or 5-methyl-THF without requiring DHFR, making it particularly useful for counteracting the effects of chemotherapeutic agents (38,39)

In vitro investigation: impact of iron supplementation on dihydroartemisinins antimalarial efficacy To explore the mechanism underlying the potent antimalarial effect of dihydroartemisinin (DHA) when interacting with iron, we analyzed how iron supplementation influences DHAs efficacy against Plasmodium falciparum 3D7 at 3, 9, and 24 hpt (Fig

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10.1126/science.1224820 2 AskarovaS.UmbayevB.MasoudA.-R.KaiyrlykyzyA.SafarovaY.TsoyA.et al (2020)

Kurian P, Dunston G, Lindesay J (2014)

At the hypothalamic level, TRH decrease is largely mediated by a T 3 -induced feedback mechanism in illness