These findings demonstrate that VPA exposure induces significant microglial activation in the hippocampal CA1 region, which is effectively attenuated by hCiPSC-NSCs treatment, indicating a substantial reduction in neuroinflammatory responses
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Berberine promotes M2 macrophage polarisation through the IL-4-STAT6 signalling pathway in ulcerative colitis treatment
Orthopedics 42 , e460e464 (2019)
In agreement with this, the ability of PA to protect cells against oxidative stress has been associated with inhibited ROS generation, increased GSH levels, and decreased lipid peroxidation (MDA), as shown in several studies (Lee et al., 2005