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doi: 10.1111/j.1365-2710.1992.tb01315.x

In other experiments, the therapy was administered once at a later ligation time after additional colon obstruction (IC + OB rats)

After the formation of an epoxyallylic radical, the enzyme hydroperoxide lyase, which should be more accurately termed a hemiacetal synthase, converts the epoxy intermediate into a vinyl ether and thence to a short-lived hemiacetal, which spontaneously decomposes into two short chain fragments, i.e., cis -3-hexenal and 12oxo- cis -9-dodecenoic acid, though the positions and geometry of the double bonds may change by chemical or enzymatic isomerization