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*The New England Journal of Medicine*, 357(3), 266-281

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Contraindication Signals Standard conservative practice excludes anyone with active gastrointestinal disease, type 1 diabetes, prior pancreatitis, medullary thyroid carcinoma history, or active cancer from any retatrutide protocol

Projected Weight Loss by Starting Weight Based on Phase 3 data (12 mg dose, 68 weeks, 28.7% mean weight loss): averages based on the TRIUMPH-4 mean

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An approach based on targeted elimination of senescent cells allows the body to reactivate its natural function without the need for artificial replacements