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Consequently, taking a highly bioavailable glutathione supplement is essential so that the nutrient reaches the cells that need it most

Figure 2 4.3.2 Amplification of immune responses by released intracellular components following ferroptosis When ferroptosis leads to the rupture of chondrocytes or synovial cells, the oxidized lipid byproducts, iron ions, and damage-associated molecular patterns (DAMPs) that leak from these cells are detected by nearby immune cells

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Cell Death Dis 15 , 534 (2024)

From baseline (week 0) to end of treatment (week 68)

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