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Jul 2019;36(7):1379-1385

[113] demonstrated that in the eyes of aged mice, the increased signaling of the STAT3 pathway induced the M2 polarization of macrophages, thus enhancing vascular proliferation and subsequently the formation of angiogenesis

Due to its high in vitro anti-inflammatory activity and lack of cytotoxicity, compound 13 appears to be a promising candidate for further research as a potential lead compound for targeting inflammation

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