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The lack of intrinsic factor is most commonly due to autoimmune gastritis, which causes an autoimmune attack on the parietal cells that create it in the stomach

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One of the few studies in human medicine to address carnosines effect on CVD, a randomized placebo-controlled clinical trial, found that adding carnosine (500 mg/day for 6 months) to established treatments for chronic heart failure improved cardiopulmonary stress tests, 6-min walk test scores and quality of life [100]

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