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Concerning signs that require medical attention include: Spreading redness larger than a few inches Red streaks Severe or worsening pain Fever or chills Hives away from the site Facial or throat swelling Any breathing difficulty When symptoms worsen rather than improve, document the site with a photo and contact your clinician promptly so they can assess for infection or a true allergic response

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Pale or yellowish skin: This could be a sign of anemia due to a decrease in red blood cell production caused by a deficiency

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Contraindication Should not be used in the patients on Levodopa therapy and hypersensitivity to any of the active ingredients

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