Acioglu C, Mirabelli E, Baykal AT, Ni L, Ratnayake A, Heary RF, et al
Addition of 0.5 1 .0% -glucan (isolated from the fungus Aureobasidium pullulans) into the diet of ovalbumin-allergic mice resulted in a decline of specific IgE, with coincidental increase of production of IFN- and IL-12 from splenocytes in vitro after stimulation with concanavalin A.32 The effect depends on the application method and on the form of applied -glucan, because a stronger effect was noticed with increasing degree of dispersion.32,33 Correspondingly, peroral application of herbal extract with -glucan content (from Ganoderma lucidum) resulted in a reduction of clinical symptoms in mice allergic to peanuts34 and house dust mite allergens.35 In the animal model of atopic eczema, application of paramylon (-glucan from the unicellular flagellated protist Euglena gracilis) caused responses of both TH1 and TH2 to be blocked
A., and Pathak D
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Hypoglycemic and antihyperglycemic activity of the leaves of MO might be due to the presence of terpenoids, which are involved in the stimulation of -cells and the subsequent secretion of insulin
