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As of 2025, retatrutide has not received MHRA or EMA marketing authorisation in the UK and remains in Phase 3 clinical trials

By targeting specific receptors and pathways, the compound can often achieve the desired therapeutic effects with a reduced risk of unintended consequences

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Scott Butsch, director de medicina de la obesidad del Instituto Baritrico y Metablico de la Clnica Cleveland

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Animal Studies: Strong Results in Obese Rodent Models The foundational animal work was conducted in obese Zucker rats and ob/ob mice, two standard models for studying obesity