found that 45% of East Asians have a deficiency in ALDH2 enzymatic activity, leading to ALD and increasing the risk of hepatocellular carcinoma (HCC) (Wang et al., 2021)
Other gastrointestinal/digestive adverse reactions reported by tadalafil recipients and more frequently than placebo included nausea (1-11%), viral gastroenteritis (3-5%), gastroesophageal reflux (1-3%), abdominal pain (1-2%), and diarrhea (1-2%)
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The fiber acts as a prebiotic, feeding beneficial gut bacteria, promoting a healthy internal ecosystem
