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Increasing Dose: What the Evidence Shows A common misconception is that tolerance means the drug no longer works

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Some patients also benefit from cycling their eating patterns or temporarily increasing calorie intake for a week to reset metabolic signalinga strategy worth discussing with your prescriber

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Incretin-based therapy: a powerful and promising weapon in the treatment of type 2 diabetes mellitus

Hadjittofi C, Feretis M, Martin J, Harper S, Huguet E