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Typically, patients of our weight loss program in Torrance, California who start FDA-approved GLP-1 medications like Ozempic and Wegovy lose an average 15% of their weight when combined with diet and exercise

Brain Res 680:1622 Langeveld CH, Schepens E, Jongenelen CA, Stoof JC, Hjelle OP, Ottersen OP, Drukarch B (1996) Presence of glutathione immunoreactivity in cultured neurones and astrocytes

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This increase in energy expenditure, along with enhanced glycogen metabolism, is a plausible mechanism for the weight loss observed with GLP-1RAs

AS, ED, DN, DA, RB, and MN edited the manuscript

Wegovy may be more expensive and may not be covered by insurance, while Ozempic is more likely to be covered for diabetes treatment