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Specifically, in non-diabetic females with a BMI exceeding 35 kg/m 2 , prenatal administration of metformin resulted in reduced maternal weight gain without impacting newborn birth weight (Syngelaki et al., 2016)

doi: 10.7326/0003-4819-116-2-103 50 BarndenLRShanZYStainesDRMarshall-GradisnikSFineganKIrelandTet al

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There is also a connection between alcohol consumption and APAP hepatotoxicity[43], and again the presumed mechanism is an increase in activity of one or more P450 enzymes[46, 47]

I'd say that this sounds like B12 deficiency, but there are other things that it could be

Near fatal asthma: clinical and airway biopsy characteristics