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4.5
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Description

Constipation and other GI side effects are consistently worse when doses are escalated quickly

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The table lists exenatide, marketed as Byetta, approved in 2005 for type 2 diabetes

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(Lond) 3 (1), 136

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Tirzepatide produced greater average weight loss in a direct 72-week obesity trial, while semaglutide has a cardiovascular risk-reduction indication for certain adults

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Woodcock and LaVange, 2017)

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