Long-term berberine use, specifically, has limited safety data
According to FAIR Health, prescriptions for GLP-1 drugs to treat overweight or obesity rose 587% from 2019 to 2024
It works by producing short-chain fatty acids that stimulate colonic motility
As a result of their research, the group in Copenhagen independently came to essentially the same conclusion as the Boston team that the biological activity of GLP-1 lay in a truncated form of the peptide which they identified as starting at residue 78 on the peptides sequence (Holst 2019
In gestational diabetes, insulin (often with metformin) is the standard when diet alone doesnt keep glucose in target range
Advanced analytical techniques are enabling researchers to track the compound's effects on global metabolite profiles, revealing complex interactions between NAD+ metabolism, methylation cycles, and other metabolic pathways that were previously unappreciated