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SKU: 98203501997
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Jerremalm et al., 2006;Corti et al., 2010)

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Early-phase trials (e.g., NCT00433576, NCT00256334) demonstrated acceptable safety and tissue bioavailability at moderate doses, whereas high-dose formulations such as SRT501 in multiple myeloma (NCT00920556) caused renal toxicity, highlighting dose-related safety concerns