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2 Adenosine signaling in the liver Caffeine is structurally similar to adenosine and is a non-selective adenosine receptor (AR) inhibitor that competently inhibits adenosine both in vitro and in vivo (van Dam et al., 2020)

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We evaluated profiles at hour 2 rather than earlier in perfusion as we observed that renal blood flow took 2 h to stabilise (Fig

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