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Discuss supplementation with your GP first, especially if you take regular medications or have other health conditions, and prioritise evidence-based lifestyle changes such as weight loss and dietary modification

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Most studies rely on single-parameter assessments, and a comprehensive model linking SIRT1 activation efficiency with phenotypic improvement is lacking

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However, current research suggests that daily doses of up to 4 grams are generally safe, even in conjunction with antiplatelet or anticoagulant therapies (82)

Oxidative stress biomarkers (8-isoprostane) decreased by 35%