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Visible physical changes (body composition, skin texture) appear at 8-12 weeks

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Financial support of this work was provided by grants from the French ANR and Hungarian NIH (2010-INT-1101-01) and from the Ligue Nationale contre le Cancer (Team certified Ligue 2012 and Comit du Rhne 2016-2017)

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Her investigations in another hospital with abdominal CT revealed wall thickening and soft tissue mass at the rectosigmoid junction and a mass shadow in the right lobe of the liver, suggesting liver metastasis of colon cancer in the right lobe

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