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ADSC-EVs have been demonstrated to ameliorate ALI through mechanisms that include immunomodulation of alveolar macrophages and protection of the pulmonary endothelial barrier

In non-human research, it has shown relevance in the regulation of gene expression tied to regeneration, collagen production, and oxidative stress recovery

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73 TamuraY.KimbaraY.YamaokaT.SatoK.TsuboiY.KoderaR.et al (2017)

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For example, a tri-functional copper-based MOF nanozyme developed by Dong et al.not only generates ROS but also modulates the redox environment, overcoming chemotherapy resistance in CRC and providing a new therapeutic strategy for future clinical applications [101]