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Histopathological evaluation was performed using a semi-quantitative scoring system previously described in the literatre.23 Each slide was examined independently by two blinded histologists who were unaware of the experimental groups

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7.4.2 Vascular cognitive impairment Given the strong indication of reduced risk of vascular dementia, dedicated trials are necessary to evaluate semaglutide in patients with established vascular cognitive impairment or those at high risk

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