The Weill Cornell cohort study (255 GLP-1RA subjects, 92% women, mean age 64) found that greater annualized hip bone loss was concentrated in patients without diabetes - exactly the demographic of postmenopausal women using GLP-1s purely for weight management
But that doesnt mean you have to stop taking Type 2 diabetes medication or weight loss medication
Over time, oxidative stress can accelerate aging and make the body more susceptible to illness
Furthermore, a 2023 study reported that lower levels of vitamin B12 are associated with increased symptoms of insomnia
36.Schuemie MJ, Cepeda MS, Suchard MA, et al
In other words, the 1 in 10 people getting worse after starting with the B12 shots may just be the result of one of the other coexisting illnesses getting worse