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At week 40, the average change in HbA1c levels from the baseline was -2.40% for the 10-mg tirzepatide group and -2.34% for the 15-mg tirzepatide group, compared to -0.86% for the placebo group

Jones KL, Rigda RS, Buttfield MDM et al (2019) Effects of lixisenatide on postprandial blood pressure, gastric emptying and glycaemia in healthy people and people with type 2 diabetes

In November 2025, we were granted a provisional patent for a multi-stage oral delivery system that overcomes the destructive acidic environment of the stomach

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Accordingly, it is well-established that DPP-4 does play a pivotal role in the initial inactivation of both endogenous incretin hormones