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Unlike sitagliptin, which allows the body to use its own limited supply of GLP-1, these medications deliver a synthetic or recombinant version of the hormone that provides a much stronger and more sustained signal

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Cardiovascular and metabolic diseases including obesity remain important areas of unmet medical need, and we plan to continue applying our global capabilities to advance a pipeline of investigational treatments that have the potential to fill critical gaps in patient care, including continued development of our oral GIPR antagonist candidate and other earlier obesity programs, said Chris Boshoff, MD, PhD, Chief Scientific Officer and President, Research and Development at Pfizer

In this case, consider asking your doctor about Wegovy (semaglutide approved for weight loss), which some plans cover for obesity treatment, or explore cash-pay options

Novo Nordisk offers savings programs for certain brand-name drugs, but they come with eligibility requirements

The discovery of Alzheimer's disease