It also has been demonstrated that prolactin induces increased expression of Pparg , Xbp1s , and GLUT4 in visceral and subcutaneous adipose tissue and elevated circulating adiponectin levels thereby increasing insulin sensitivity in mice (65)
Oncogene 37 , 450460 (2018)
The trial also showed improvements in: Blood pressure Triglycerides Inflammatory markers Meanwhile, the SURMOUNT-2 trial , which studied patients with type 2 diabetes, demonstrated similar benefits, proving GLP-1s are effective even in populations with metabolic challenges
doi: 10.1002/mrd.1080420311
Clinical trials on Semalglutide (the generic name) began in 2008, as a solution for Type 2 Diabetes
Experts say its common for people to have side effects with GLP-1s