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In the early stage, right after the bite, a characteristic bull's-eye rash called erythema migrans appears in roughly 70-80% of cases

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REDEFINE Clinical Trial Program Overview The REDEFINE program is a comprehensive Phase 3 clinical trial initiative evaluating CagriSema across diverse populations and settings: Expected Completion: The REDEFINE program is anticipated to complete enrollment and report results between 2024-2026, providing comprehensive data to support regulatory submissions worldwide

The gut-brain axis is a conduit for crosstalk between gut microbiota and the CNS, with microbial dysbiosis impairing sleep quality, and vice versa (Lin et al., 2024)

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