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Current clinical strategies for the management of PDN include glycolic control and treatment with drugs such as tricyclic compounds, serotonin noradrenalin reuptake inhibitors, -lipoic acid, anticonvulsants, opiates, membrane stabilizers and topical capsaicin

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We detail how these -glutamylcyclotransferases degrade GSH, thereby modulating cellular redox balance and integrating diverse stress signaling pathways

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[DOI] [PubMed] [Google Scholar] 78.Shi Y, Sun X, Zhang L, Sun K, Li K, Li Y, et al

When the skin heals, it may produce excess melanin, leading to dark patches or spots