JAMA 316 , 500508 (2016)
However, experts quoted in a July 29 PBS article warned that these supplements do not come close to matching the effectiveness of real GLP-1 agonists such as semaglutide (sold under the brand names Ozempic and Wegovy) and tirzepatide (sold as Mounjaro and Zepbound)
GLP-1, or glucagon-like peptide-1, is a hormone that your body produces naturally
Neuropeptides 94 , 102250 (2022)
However, available interviews and media coverage consistently point to a non-surgical approach built on gradual, long-term habit change rather than quick medical solutions
The 12 week phase 1b clinical trial for patients with type 2 diabetes from December 18, 2018 to December 28, 2020 showed that the three high-dose groups of Retatrutide were significantly better than the placebo control group in reducing blood sugar and glycosylated hemoglobin (HbA1c), and showed a dose related weight loss effect