El uso prolongado puede elevar los niveles de TMAO, lo que se ha relacionado con un posible riesgo cardiovascular
"For other patients, that may be what they need to get healthy
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(2004), Restorative increases in serum testosterone levels are significantly correlated to improvements in sexual functioning
These effects of Pycnogenol on joints can be explained by previous findings, showing that regular intake of Pycnogenol leads to a potent decrease of pro-inflammatory markers like NF-B and COX-enzymes, as well as a decline in the release of matrix metallopeptidase (MMP) enzymes, that are responsible for destroying cartilage in joints (71)
But some conditions, such as liver disease, cause your body to retain this vitamin