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Base excision repair enzymes like OGG1 and APE1 show increased expression

Therefore, regulating the redox state by intracellular GSH is crucial for maintaining cellular functions under physiological and pathological conditions

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The expression of these enzymes is known to vary appreciably amongst individuals and hence inter-individual differences in susceptibility would be anticipated

Pal PK, Sarkar S, Chattopadhyay A, Tan DX, Bandyopadhyay D

Improvements and impacts of GRCh38 human reference on high throughput sequencing data analysis