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Lee SG, Ro HS, Hong SP, Kim EH, Sung MH (1996) Production of L-DOPA by thermostable tyrosine phenol-lyase of a thermophilic Symbiobacterium species overexpressed in recombinant Escherichia coli

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Participants showed significant reductions in monthly migraine days and migraine severity over the treatment period, alongside weight loss and metabolic improvements