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GLP-1 drugs may offer promise for people who are managing both psoriatic arthritis and other conditions like diabetes or weight issues
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Specifically, retatrutide simultaneously activates three distinct hormone receptors: GLP-1 (glucagon-like peptide-1) receptors promoting insulin secretion, reducing appetite, and slowing gastric emptying GIP (glucose-dependent insulinotropic polypeptide) receptors enhancing insulin response and supporting fat metabolism Glucagon receptors increasing energy expenditure and promoting hepatic fat breakdown It is important to note that glucagon receptor activation can, in isolation, raise blood glucose levels
Its important for patients to understand that GLP-1 medications are not a skinny shot, but a tool designed to support metabolic health through long-term weight management
For some people, this means purchasing the drug from an international manufacturer or compounding pharmacy to access non-standard doses, explains Mitch Biermann, MD, PhD , an internal and obesity medicine specialist at Scripps Clinic
