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GLP-1 ameliorated MG-induced mitochondrial dysfunction, ATP depletion, and suppressed prolonged AMPK activation Steady decline in ATP production was observed in MG-treated cells (Fig

It is estimated that AD may affect about 6% of the people of the world over 65 and 40% of people over 85 [31]

We detected different concentrations of ATP, NAD + , NADH, NAPD + , NADPH, as well as 62 other metabolites, and 19 isotopically labelled metabolites between the mutant and the wild-type strains

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