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NAC dose was titrated from 1200 mg per day to 3000 mg per day, and duration of the trial was 12 weeks

Inside the cell, ATP is highly unstable on its own and must bind to a magnesium ion to form the biologically active "Mg-ATP complex." Almost all enzymes that synthesize or utilize ATP require it to be in this complexed form to function properly

An important advantage of this therapy is that it does not significantly increase hormones such as cortisol or prolactin, which are often associated with unwanted side effects

The main reason: the lack of randomized controlled clinical trials in humans

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4c), an observation that is in agreement with our biochemical analyses (Table 1)