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An overdose may cause gastrointestinal effects, including nausea, vomiting or diarrhoea, which may lead to dehydration

35 Regional prevalence varies significantly due to ethnic, genetic, and lifestyle factors, with the lowest rates observed in Western Europe and the highest in Latin America, ranging from 25.1% to 44.3%

The overexpression of GlcNAcase or the inhibition of GlcNAc modification increases the expression of SERCA2a, the ablated sarcoplasmic reticulum Ca 2+ leakage, improved cardiac contractility, and reduced arrhythmia events (56)