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Over-the-counter anti-diarrheal medications like loperamide may provide relief, though patients should confirm with their healthcare provider that these are appropriate for their specific situation before use

Neeland, MD, FAHA, FACC, director of cardiovascular prevention and co-director of the Center for Integrated and Novel Approaches in Vascular-Metabolic Disease for University Hospitals Harrington Heart & Vascular Institute and associate professor of medicine at Case Western Reserve University School of Medicine, told Cardiology Today

It is a pharmacological necessity

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Compared to GSH_a, the higher RMSF values of residues surrounding GSH_b reflect its greater conformational flexibility

In peptide-leaning design spaces, reviews emphasize that non-proteinogenic substitutions can shift stability and permeability