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Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1

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(ii) Gametes and embryos from patients with endometriosis are exposed to an ROS-rich pro-oxidant microenvironment in the fallopian tubes, the ovary, and the follicle

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